diff --git a/pkgs/tools/graphics/pngquant/default.nix b/pkgs/tools/graphics/pngquant/default.nix
index b2b0691718a9..bb0ef8581250 100644
--- a/pkgs/tools/graphics/pngquant/default.nix
+++ b/pkgs/tools/graphics/pngquant/default.nix
@@ -14,6 +14,8 @@ stdenv.mkDerivation rec {
 
   preConfigure = "patchShebangs .";
 
+  configureFlags = lib.optionals (!stdenv.isi686 && !stdenv.isx86_64) [ "--disable-sse" ];
+
   nativeBuildInputs = [ pkg-config ];
   buildInputs = [ libpng zlib lcms2 ];