diff --git a/pkgs/top-level/perl-packages.nix b/pkgs/top-level/perl-packages.nix
index 67be5a8cfe4d..da3aea3fd807 100644
--- a/pkgs/top-level/perl-packages.nix
+++ b/pkgs/top-level/perl-packages.nix
@@ -17730,6 +17730,10 @@ with self;
       url = "mirror://cpan/authors/id/T/TO/TODDR/IO-Tty-${version}.tar.gz";
       hash = "sha256-sVMJ/IViOJMonLmyuI36ntHmkVa3XymThVOkW+bXMK8=";
     };
+    # Fix dynamic loading not available when cross compiling
+    postPatch = lib.optionalString (stdenv.hostPlatform != stdenv.buildPlatform) ''
+      sed -i '/use IO::File/d' Makefile.PL
+    '';
     doCheck = !stdenv.hostPlatform.isDarwin; # openpty fails in the sandbox
     meta = {
       homepage = "https://github.com/toddr/IO-Tty";