diff --git a/nixos/modules/system/boot/binfmt.nix b/nixos/modules/system/boot/binfmt.nix
index d16152ab9dec..9639d67abe61 100644
--- a/nixos/modules/system/boot/binfmt.nix
+++ b/nixos/modules/system/boot/binfmt.nix
@@ -281,7 +281,7 @@ in {
   };
 
   config = {
-    boot.binfmt.registrations = builtins.listToAttrs (map (system: {
+    boot.binfmt.registrations = builtins.listToAttrs (map (system: assert system != pkgs.system; {
       name = system;
       value = { config, ... }: let
         interpreter = getEmulator system;